Jacob Stuckey, Ph.D.

Jacob Stuckey, Ph.D.

Director, Biochemistry and Chemical Biology

EDUCATION
Ph.D., Pharmaceutical Sciences, University of North Carolina at Chapel Hill
B.S., Chemistry, Lenoir-Rhyne University

PREVIOUS EXPERIENCE
Constellation Pharmaceuticals

Jake’s Flare characteristics: Innovation and rigor.

Jake is passionate about blending mechanistic biochemistry with state-of-the-art drug discovery and chemical biology approaches. One of the architects of the Switch Site Framework, Jake is excited to help empower the team to discover the next wave of transcription factor medicines.

He has contributed to numerous drug discovery efforts, including co-invention of CPI-0209, Constellation Pharmaceuticals’ second generation EZH2 inhibitor that is currently in clinical trials.

When he’s not busy at Flare, Jake is busy trying to keep up with his two children.

WHAT MAKES YOU EXCITED TO ‘BRING IT’ EVERY DAY AT WORK?

The opportunity to provide patients with a treatment option targeting the genetic cause of their condition.

WHAT SPARKED YOU TO JOIN FLARE?

I saw an opportunity to rewrite the chapter on transcription factor drug discovery.

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