ON THE PATH
TOWARD THE POSSIBLE

At Flare Therapeutics, we are building a pipeline of drug discovery programs from select transcription factors with robust genetic and biologic validation, initially focused on precision oncology. With our ability to integrate TF structure and genetics alongside our proprietary, context-dependent electrophilic libraries, we can uniquely identify druggable pockets that are central to TF conformational control in order to tune their function. This leads to our highly differentiated pipeline of drug programs that opens a new path for targeting the central genetic drivers of cancer and other diseases.

Further, we are applying our discovery engine to early discovery programs in metabolic, neurology, immunology/inflammation and rare genetic disorders driven by transcriptional dysregulation.